3H-Vitamin A and Rat Skin

Vitamin A and the Skin

Vitamin A (vit. A) is essential for normal differentiation and maintenance of • epithelial tissues in skin and mucous membranes, vision (retinaldehyde), reproduction (retinol), and embryonic morphogenesis. Retinoids (compounds with biological activities similar to those of vit. A) are used • as therapeutic agents for hyperkeratotic and parakeratotic skin diseases, acne and acne-related disorder...

Synthesis of LHydroxy [6-3H]vitamin D, and Its Metabolism to lar,25-Dihydroxy [6-3H]vitamin D, in the Rat*

loc-Hydroxy[6-3H]vitamin D, has been synthesized with a specific activity of 4 Ci/mmol, and its metabolism in rats has been studied. It is rapidly converted to ln,25-dihydroxy[6-3H]vitamin D, in uiuo. Following an intravenous or oral dose, a maximal concentration of loc,25-dihydroxy[6-3H]vitamin D, is found 2 and 4 hours, respectively, before the maximal intestinal calcium transport response is...

Vitamin D and skin diseases: A review.

Vitamin D, originally associated with rickets and osteomalacia, has recently been shown to have a role in a number of medical and dermatological diseases. It has been found that vitamin D receptors and the enzymatic machinery capable of converting circulating 25-hydroxyvitamin D [25(OH)D] to the active 1,25-hydroxyvitamin D [1,25(OH)D] is present in most cells in the body including the skin. It...

Laser Soldering of Rat Skin Using a Controlled Feedback System

Introduction: Laser tissue soldering using albumin and indocyanine green dye (ICG) is an effective technique utilized in various surgical procedures. The purpose of this study was to perform laser soldering of rat skin under a feedback control system and compare the results with those obtained using standard sutures. Material and Methods: Skin incisions were made over eight rats’ dorsa, which w...

Skin Cancer and Vitamin D